KMID : 1234520070020010048
|
|
Korean Journal of Urogenital Tract Infection Inflammation 2007 Volume.2 No. 1 p.48 ~ p.52
|
|
Uropathogenic Escherichia coli Infection and Host Response
|
|
Lee Gil-Ho
|
|
Abstract
|
|
|
Urinary tract infections are a result of interactions between the uropathogen and the host. Successful infection of the urinary tract is determined in part by the virulence factors of the bacteria such as type 1 fimbriae and/or P fimbriae, the inoculum size, and the inadequacy of host defense mechanisms. Detection of microorganisms through microbe-associated molecular patterns by Toll-like receptors is crucial to trigger protective innate immunity. A rapid cytokine response was observed when Escherichia coli bacteria infected the epithelial cells with production of interleukin-1©¬ (IL-1©¬), IL-6, and IL-8. These factors play a role in determining the damage to the urinary tract.
|
|
KEYWORD
|
|
Urinary tract infection, Host, E. coli
|
|
FullTexts / Linksout information
|
|
|
|
Listed journal information
|
|
|